Most Common Side Effects

Learn about the most common side effects of Savella.

The most common side effect associated with Savella treatment is nausea. In clinical trials, patients experiencing nausea described it as mild to moderate. Approximately 6% of those taking Savella discontinued due to nausea versus 0.6% for those taking a sugar pill (placebo). You may find taking Savella more tolerable if you take it with a meal.

Other common side effects are headache, constipation, dizziness, insomnia, hot flush, hyperhidrosis (excessive sweating), vomiting, palpitations, increased heart rate, dry mouth, and hypertension.

In clinical trials, Savella was not shown to be associated with weight gain or weight loss. Patients in clinical trials who took Savella had an average weight loss of 1.76 lbs. compared to patients in the placebo group who lost an average of .44 lbs.

This is not a complete list of side effects. Please see the Important Risk Information about Savella. And ask your healthcare provider about possible risks and side effects.

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